Products of the reaction of 2-chloro-6-thio-7-methyl-purine with amines |
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| Authors: | P M Kochergin E V Aleksandrova V S Korsunskii |
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| Institution: | (1) Center for the Chemistry of Medicnal Compounds, All Russian Chemico-Pharmaceutical Science Research Institute, 119815 Moscow;(2) Zaporozh'ye State Medicinal University, 330074 Zaporozh'ye, Ukraine |
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| Abstract: | Treatment of 2-chloro-6-thio-7-methylpurine with aniline, piperidine, or morpholine with heating in DMF gives 2-phenylamino(piperidino or morpholino)-6-thio-7-methylpurine. The scheme for the formation of the side products 2,6-dithio-and 2,6-dipiperidino-7-methylpurine is discussed.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 82–84, January, 2000. |
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| Keywords: | chloropurine thiopurines chlorothiopurines aminopurines aniline morpholine piperidine |
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