A Novel Preprocessing Algorithm for Three-Way HPLC Data |
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Authors: | Bi Xian Tonghua Li Chen Kai Tongcheng Cao Jianrong Huang Yunpeng Qi |
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Affiliation: | (1) Department of Chemistry, Tongji University, Shanghai, 200092, China;(2) College of Pharmacology, Second Military Medical University, Shanghai, 200433, China |
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Abstract: | Orthogonal signal correction (OSC) was a data preprocessing algorithm. It ensured that the filtered information was irrelevant to concentration data while using it to filter the noise from the original data. This paper extended the OSC application range from two-way data to three-way data. Two drug data sets, Enoxacin, Norfloxacin, Ciprofloxacin and Betamethasone, cortisone acetate, prednisone acetate, showed that the application of the OSC algorithm to three-way HPLC data was feasible and needed further research. |
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Keywords: | orthogonal signal correction OSC three-way PLS HPLC |
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