A microwave-assisted synthesis of phenanthroperylene quinones as exemplified with hypericin |
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| Authors: | Stefan Aigner Heinz Falk |
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| Institution: | (1) Institute of Organic Chemistry, Johannes Kepler University, Linz, Austria |
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| Abstract: | The synthesis of hypericin, one of the most important phenanthoperylene quinones used in photodynamic therapy, could be highly improved by using either a microwave-assisted dimerization of emodinanthrone, or a mixed dimerization of emodinanthrone with emodin in the presence of potassium t-butoxide as the key-step. |
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| Keywords: | Hypericin Emodin Emodinanthrone Synthesis Microwave irradiation |
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