Indole derivatives

An improved method is proposed for obtaining skatyl- and substituted skatylmalonic esters by the alkylation of sodiomalonic esters with gramme methiodide in dimethylformamide in an inert-gas atmosphere, which leads to yields exceeding 90%. To obtain a skatylmalonic ester uncontaminated with the diskatylmalonic ester a method is proposed which involves the catalytic hydrogenation of a skatylidenemalonic ester over Pd/CaCO₃; yield 96%.For Communication LXXXVI, see [1].Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1512–1514, November, 1973.