Anti-inflammatory activity of alkaloids: an update from 2000 to 2010 |
| |
| Authors: | Souto Augusto Lopes Tavares Josean Fechine da Silva Marcelo Sobral Diniz Margareth de Fátima Formiga Melo de Athayde-Filho Petrônio Filgueiras Barbosa Filho José Maria |
| |
| Institution: | Laboratory of Pharmaceutical Technology, Federal University of Paraiba, 58051-900, Jo?o Pessoa-PB, Brazil. augustosouto@gmail.com |
| |
| Abstract: | Many natural substances with proven anti-inflammatory activity have been isolated throughout the years. The aim of this review is to review naturally sourced alkaloids with anti-inflammatory effects reported from 2000 to 2010. The assays were conducted mostly in vivo, and carrageenan-induced pedal edema was the most used experimental model. Of the 49 alkaloids evaluated, 40 demonstrated anti-inflammatory activity. Of these the most studied type were the isoquinolines. This review was based on NAPRALERT data bank, Web of Science and Chemical Abstracts. In this review, 95 references are cited. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
