Direct synthesis of unprotected 4-aryl phenylalanines via the Suzuki reaction under microwave irradiation |
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| Authors: | Gong Yong He Wei |
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| Affiliation: | Drug Discovery, Johnson & Johnson Pharmaceutical Research & Development, L.L.C, Welsh & McKean Roads, Spring House, Pennsylvania 19477-0776, USA. ygong@prdus.jnj.com |
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| Abstract: | [formula: see text] 4-Aryl phenylalanines were prepared as free amino acids from the Suzuki coupling of 4-borono phenylalanine with aryl halides in high yields within 5-10 min under microwave irradiation. |
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