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Copper‐Promoted Conversion of Aromatic Amines into Trifluoromethylated Arenes: One‐Pot Sandmeyer Trifluoromethylation |
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| Abstract: | A simple copper‐promoted one‐pot Sandmeyer trifluoromethylation of aromatic amines with Langlois’ reagent has been demonstrated. The reaction is performed in mild reaction conditions under an air atmosphere with good substrate scope and functional group compatibility. It provides an alternative and straightforward synthetic approach to access a variety of trifluoromethylated arenes. |
| Keywords: | copper sandmeyer trifluoromethylation aromatic amine langlois’ reagent trifluoromethylated arene |