Abstract: | Many materials as immune adjuvant are researched to help raise immnogenicity of subunit vaccines. Among them, peptide‐based hydrogels are gradually coming into notice because of their application in drugs delivery, cancer cell inhibition, vaccine adjuvants and detection of important analytes. In this work, we introduced a novel aromatic capping group based on indole to construct short peptide‐based supramolecular hydrogelators Indol‐GFFY and Indol‐GD FD FD Y and demonstrated their potential applications as vaccine adjuvants. |