| Abstract: | The simultaneous voltammetric determination of melatonin (MT) and pyridoxine (PY) has been carried out at a cathodically pretreated boron‐doped diamond electrode. By using cyclic voltammetry, a separation of the oxidation peak potentials of both compounds present in mixture was about 0.47 V in Britton‐Robinson buffer, pH 2. The results obtained by square‐wave voltammetry allowed a method to be developed for determination of MT and PY simultaneously in the ranges 1–100 μg mL?1 (4.3×10?6–4.3×10?4 mol L?1) and 10–175 μg mL?1 (4.9×10?5–8.5×10?4 mol L?1), with detection limits of 0.14 μg mL?1 (6.0×10?7 mol L?1) and 1.35 μg mL?1 (6.6×10?6 mol L?1), respectively. The proposed method was successfully to the dietary supplements samples containing these compounds for health‐caring purposes. |
