首页 | 本学科首页   官方微博 | 高级检索  
     检索      


Cu(I)‐catalyzed Green Synthesis of Propargyl Amines Decorated with Carbazole Moiety by A3 ‐Coupling
Abstract:A series of novel N ‐alkylcarbazol–propargylamine hybrids were designed and synthesized by CuIBr ‐catalyzed A3 ‐coupling of N ‐octylcarbazol‐3‐carbaldehyde, amines, and alkynes. The tri‐substituted propargyl amines decorated with carbazole moiety were obtained under solvent‐free conditions in good to moderate yields. Furthermore, the scope of the method was studied, which was found to be applicable to primary aliphatic and aromatic amines. Also, a large variety of substituents both on alkynes and anilines are well tolerated.
Keywords:   A3   ‐coupling  Propargyl amines  Cu‐catalysis  Carbazole  Green synthesis
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号