Pyrimidines |
| |
Authors: | M A Mikhaleva G N Chernikova V P Mamaev |
| |
Institution: | (1) Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Academy of Sciences of the USSR, 630090 Novosibirsk |
| |
Abstract: | 3-Arylbenzof]quinazolines were obtained by reaction in acetic or propionic acid of -naphthylamine, ammonia, and aromatic aldehydes containing an NR2 or OH group. A mechanism is proposed for the formation of monoarylbenzof]quinazolines from the corresponding intermediate 1,3-diaryldihydrobenzo f] quinazolines by acid cleavage of the C-aryl bond in the 1 position. This mechanism was confirmed experimentally by establishment of the fact of cleavage of 1,3-bis (p-methoxyphenyl)-1,2-dihydrobenzof] quinazoline when the acidity of the medium is increased; 3-(p-methoxyphenyl) benzo f] quinazoline and anisole were obtained in the reaction products. Condensation in the presence of formic acid gave -arylidene-N-formyl- -naphthylamines rather than arylbenzo f] quinazolines.See 1] for communication LXIV.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1265–1271, September, 1978. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|