Site-selective depurination by a periodate-dependent deoxyribozyme |
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Authors: | Höbartner Claudia Pradeepkumar P I Silverman Scott K |
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Institution: | Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, USA. |
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Abstract: | A deoxyribozyme is identified that mediates the site-selective depurination of its 5'-terminal guanosine nucleotide using periodate (IO(4)-) as an obligatory cofactor. |
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