Synthese de F-alkyl-2 hydroxy-4 quinoleines

F-alkynes and F-alkynyl esters are versatile intermediates for the synthesis of F-alkyl substituted heterocyclic compounds.Condensation of these compounds with aniline and its derivatives, followed by cyclisation of intermediates obtained (enamines and imines), is in fact the only way of synthesis of hydroxy-4 quinolines substituted in position 2 by a F-alkyl chain other than CF₃.