Enantioselective synthesis of β,β-dialkyl α-hydroxy γ-butyrolactones |
| |
Authors: | Sunil V Pansare Annyt Bhattacharyya |
| |
Abstract: | An ephedrine-derived morpholine dione is employed in the synthesis of chiral alkylidene morpholinones that are efficiently converted to β-substituted α,γ-dihydroxy butyramides, precursors of the corresponding butyrolactones. Enantioselective synthesis of a spiro analog of pantolactone as well as a naturally occurring pantolactone homolog is achieved with this protocol. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|