A synthesis of (−)hibaene |
| |
Authors: | Do Khac Manh Duc M Fetizon S Lazare |
| |
Institution: | Laboratoire de Synthèse Organique, Ecole Polytechnique, 91128 Palaiseau, Cedex, France |
| |
Abstract: | A total synthesis of (?)hibaene 1 is described. The key steps are a photochemical cycloaddition of vinyl acetate on the α-β unsaturated ketone 2 and a Wagner-Meerwein type rearrangement of the diols 14 and 15, which contain a highly strained cyclobutane ring. A selective esterification of the rearranged diols 22a or 22b leads to intermediates which can conveniently be transformed into (?)hibaene. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |
|