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Major metabolites of ginseng sapogenins formed by rat liver microsomes
Authors:Kasai R  Hara K  Dokan R  Suzuki N  Mizutare T  Yoshihara S  Yamasaki K
Institution:Institute of Pharmaceutical Sciences, Faculty of Medicine, Hiroshima University, Japan. rkasai@pharm.hiroshima-u.ac.jp
Abstract:Incubation of ginseng sapogenins with microsomes from rat liver resulted in formation of their 20,24-epoxides as major metabolites. Identification of the metabolites was performed by HPLC, FAB-MS and EI-MS.
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