Major metabolites of ginseng sapogenins formed by rat liver microsomes |
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Authors: | Kasai R Hara K Dokan R Suzuki N Mizutare T Yoshihara S Yamasaki K |
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Institution: | Institute of Pharmaceutical Sciences, Faculty of Medicine, Hiroshima University, Japan. rkasai@pharm.hiroshima-u.ac.jp |
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Abstract: | Incubation of ginseng sapogenins with microsomes from rat liver resulted in formation of their 20,24-epoxides as major metabolites. Identification of the metabolites was performed by HPLC, FAB-MS and EI-MS. |
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