Powder X‐ray study of racemic (2RS,3RS)‐5‐amino‐3‐(4‐phenylpiperazin‐1‐yl)‐1,2,3,4‐tetrahydronaphthalen‐2‐ol

The title compound, C₂₀H₂₅N₃O, an important precursor for the preparation of benzovesamicol analogues for the diagnosis of Alzheimer's disease, has been synthesized and characterized by FT–IR, and ¹H and ¹³C NMR spectroscopic analyses. The crystal structure was analysed using powder diffraction as no suitable single crystal was obtained. The piperazine ring has a chair conformation, while the cyclohexene ring assumes a half‐chair conformation. The crystal packing is mediated by weak contacts, principally by complementary intermolecular N—H...O hydrogen bonds that connect successive molecules into a chain. Further stabilization is provided by weak C—H...N contacts and by a weak intermolecular C—H...π interaction.