| Synthesis and Antibacterial Activity of Selenium-functionalized Poly(ε-caprolactone) |
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| 作者姓名： | Ying-Ying Li Dong Xing Xiang-Qiang Pan Jian Zhu |
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| 作者单位： | Suzhou Key Laboratory of Macromolecular Design and Precision Synthesis,Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application,State and Local Joint Engineering Laboratory for Novel Functional Polymeric Materials,Department of Polymer Science and Engineering,College of Chemistry,Chemical Engineering and Materials Science,Soochow University,Suzhou 215123,China |
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| 基金项目： | financially supported by the National Natural Science Foundation of China(No.21871200);the Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions。 |
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| 摘 要： | A selenium-functionalizedε-caprolactone was synthesized by introducing a phenyl selenide group at the 7-position.A polymer was obtained through the ring-opening polymerization of this monomer in a base/thiourea binary organocatalytic system.A living polymerization process was achieved under mild conditions.The resulting polymers had a controlled molecular weight with a narrow molecular weight distributions and high end-group fidelity.Random copolymers could be obtained by copolymerizing this monomer withε-caprolactone.The thermal degradation temperature of the obtained copolymers decreased with the increasing molar ratio of selenide functionalized monomer in copolymers,while the glass transition temperature increased.In addition,the phenyl selenide side group could be further modified to a polyselenonium salt,which resulted in a polymer with good antibacterial properties.The survival rate of E.coli and S.aureus was only 9%with a polymer concentration of 62.5μg/mL.
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| 关 键 词： | Selenium-containing polyester POLYCATIONS Antibacterial activity DEGRADABLE |
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