Europium(III) and terbium(III) chelates of quinolonecarboxylic acid derivatives as labels for immunofluorimetric assay |
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Authors: | S. V. Bel’tyukova A. V. Egorova O. I. Teslyuk |
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Affiliation: | (1) Bogatskii Physicochemical Institute, National Academy of Sciences of Ukraine, Lyustdorfskaya doroga 86, 270080 Odessa, Ukraine |
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Abstract: | Luminescence properties of Tb(III) and Eu(III) complexes of quinolonecarboxylic acid derivatives were studied. Optimal conditions of luminescence were determined, and the influence of surfactants and diethylenetriaminepentaacetic acid on the luminescence properties of the complexes was studied. It was demonstrated that species-specific immunoglobulins labeled with terbium ions can be determined with the detection limit of the lanthanide label 5 x 10-14 M. |
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