| Affiliation: | PEI Jia 1,TANG YanChun 3,XU Ning 1,LU Wei 3,XIAO ShouJun 1,2* &LIU JianNing 3* 1 State Key Laboratory of Coordination Chemistry,Nanjing National Laboratory for Microstructures,School of Chemistry and Chemical Engineering,Nanjing University,Nanjing 210093,China 2 State Key Laboratory of Bioelectronics,Southeast University,Nanjing 210096,China 3 Institute of Molecular Medicine,China |
| Abstract: | Porous silicon(PSi)was applied as a supporting substrate for stepwise covalent derivatization of undecylenic acid, N-hydroxysuccinimidyl ester(NHS-ester)and nitrilotriacetic acid(NTA).By taking the advantages of porous silicon as a supporting matrix such as high surface area to volume ratio,infrared transparency,porous semiconductors for laser desorption/ionization mass spectroscopy,and low fluorescence background,a multi-mode detection biochip prototype can be realized. We prepared such a protein microarra... |
