Tandem conjugate addition-α-alkylation of unsaturated amides. Synthesis of 1-aryltetralin lignans |
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| Authors: | G.B. Mpango V. Snieckus |
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| Affiliation: | The Guelph-Waterloo Centre for Graduate Work in Chemistry, Waterloo Campus Department of Chemistry, University of Waterloo,Waterloo, Canada N2L 3G1 |
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| Abstract: | The amide alcohols, obtained in one step from the sequential reaction of N,N-dimethylcrotonamide with dithiane anion and aryl aldehyde, were efficiently converted into the lignans galcatin and isogalcatin. |
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