Action du methyltri(n-butyl)fluorophosphorane sur les halogenures et les sulfonates d'alkyle

Monofluorophosphoranes R₃MePF are used in exchange reactions to prepare monofluorinated organic compounds. Tri(n-butyl)methylfluorophosphorane (n-Bu₃MePF), easily available, is the most reactive. In solvents of low polarity or even in non-polar solvents, it reacts at ?70° with alkyl sulphonates and halides activated by ester, ketone, or ether functions. Thus, fluorinated epoxides can be obtained directly by exchange from their chlorinated or brominated homologues.