The first chemical conversion of l-proline to l-glutamic acid |
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Authors: | Shigeyuki Yoshifuji Hideyo Matsumoto Ken-ichi Tanaka Yoshihiro Nitta |
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Institution: | School of Pharmacy, Hokuriku University, Kanagawa-machi, Kanazawa 920-11, Japan |
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Abstract: | The ruthenium tetroxide oxidation of N-acyl-l-proline esters gave the corresponding l-pyroglutamic acid derivatives in good yields with no appreciable racemization, which led to the first chemical conversion of l-proline to l-glutamic acid. |
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