Thapsigargin,constitution of a sesquiterpene lactone histamine liberator from thapsia garganica |
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Authors: | SBrøgger Christensen Ulla Rasmussen Carsten Christophersen |
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Institution: | Royal Danish School of Pharmacy, Universitetsparken 2, DK-2100 Copenhagen Denmark;Marine Chemistry Section, University of Copenhagen, The H.C. Ørsted Institute, DK-2100 Copenhagen, Denmark |
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Abstract: | The major skin irritating constituent of the root of Thapsia garganica L. has been shown to be a hexaoxygenated-C6-guaianolide esterificated with four carboxylic acids. |
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