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Investigation of interactions between dendrimer-coated magnetite nanoparticles and bovine serum albumin
Affiliation:1. Department of Radiochemistry and Colloids Chemistry, Faculty of Chemistry, Maria Curie-Sklodowska University, M. Curie-Sklodowska Sq. 3, 20-031 Lublin, Poland;2. Department of Physicochemistry of Solid Surface, Faculty of Chemistry, Maria Curie-Sklodowska University, M. Curie-Sklodowska Sq. 3, 20-031 Lublin, Poland;1. Department of Physical Chemistry, Faculty of Chemistry, University of Lodz, Pomorska 165, Lodz 90-236, Poland;2. Department of Inorganic and Analytical Chemistry, Faculty of Chemistry, University of Lodz, Tamka 12, 91-403 Lodz, Poland
Abstract:We investigated the interactions between dendrimer-coated magnetite nanoparticles (MNPs) and the protein serum albumin. The investigation was based on the fluorescence quenching of tryptophan residue of serum albumin after binding with the dendrimer-coated magnetite nanoparticles. The extent of the interactions between bovine serum albumin and dendrimer-coated MNPs strongly depends on their surface groups and pH value.
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