Preparation of magnetic poly(methylmethacrylate–divinylbenzene–glycidylmethacrylate) microspheres by spraying suspension polymerization and their use for protein adsorption |
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| Affiliation: | 1. Laboratory of Separation Science and Engineering, State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, P.O. Box 353, Beijing 100080, People''s Republic of China;2. Graduate School of the Chinese Academy of Sciences, Beijing, People''s Republic of China;1. Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada;2. Biomedical Engineering Department, The Cleveland Clinic Foundation, Cleveland, Ohio, USA;1. National Special Superfine Powder Engineering Research Center, Nanjing University of Science and Technology, Nanjing 210094, PR China;2. Beijing Sirius Technology Development Co., Ltd, Beijing 100102, PR China;1. College of Chemistry and Chemical Engineering, and Henan Key Laboratory of Function-Oriented Porous Materials, Luoyang Normal University, Luoyang 471934, China;2. School of Chemical Engineering and Energy, Zhengzhou University, Zhengzhou, China;1. Department of Chemistry, Middle East Technical University, Ankara 06800, Turkey;2. Department of Chemical Engineering and Applied Chemistry, Atilim University, Ankara 06836, Turkey;3. Central Laboratory, Middle East Technical University, Ankara 06800, Turkey;4. Polymer Science and Technology Program, Middle East Technical University, Ankara 06800, Turkey;5. Department of Biological Sciences, Middle East Technical University, Ankara 06800, Turkey;6. Micro and Nanotechnology Program, Middle East Technical University, Ankara 06800, Turkey;1. Instituto de Química, Universidade do Estado do Rio de Janeiro, Rua São Francisco Xavier, 524, PHLC, sala 310, Maracanã, 20550-900 Rio de Janeiro, Brazil;2. Departamento de Química, Universidade Federal de Ouro Preto, 35400 Ouro Preto, MG, Brazil;3. Departamento de Física e Química, Instituto de Ciências, Universidade Federal de Itajubá, Itajubá, MG, Brazil;1. Department of Materials Science, University of Patras, 26504 Rio, Greece;2. Institute for Biological and Medical Imaging, Helmholtz Zentrum München and Technische Universität München, D-85764 Neuherberg, Germany;3. Regional Centre of Advanced Technologies and Materials, Departments of Physical Chemistry and Experimental Physics, Faculty of Science, Palacky University, 783 71 Olomouc, Czech Republic;4. Department of Pharmacy, University of Patras, 26504 Rio, Greece |
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| Abstract: | Moderately uniform magnetic poly(methylmethacrylate–divinylbenzene–glycidylmethacrylate) microspheres (poly(MMA–DVB–GMA) microspheres) were prepared by spraying suspension copolymerization of methyl methacrylate, divinylbenzene and glycidyl methacrylate in the presence of Fe3O4 magnetic fluid. A protein adsorption assay indicated that these magnetic microspheres could significantly improve the capacity of protein adsorption. |
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