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Modelling magnetic carrier particle targeting in the tumor microvasculature for cancer treatment
Institution:1. Department of Mathematics, Agni College of Technology, Thalambur, Chennai 600120, Tamilnadu, India;2. Department of Mathematics, Lovely Professional University, Jalandhar 144411, Punjab, India;3. Department of Mechanical Engineering, Manipal University, Jaipur 303007, Rajasthan, India
Abstract:Magnetic drug targeting of tumors situated in the cavity of the human body is difficult because the magnetic gradients decrease rapidly with the distance from the magnets. Here computer simulations are used to investigate different techniques to focus small MPs within the microvasculature of tumors. Non-invasive methods were found to have range <15 cm whilst minimal invasive methods could be applied specifically to small tumors (<18 mm).
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