Site-directed research of magnetic nanoparticles in magnetic drug targeting |
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| Institution: | 1. Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, British Columbia, Canada;2. Biomedical Engineering Department, The Cleveland Clinic Foundation, Cleveland, Ohio, USA;1. Photonics Research Centre, University of Malaya, 50603 Kuala Lumpur, Malaysia;2. Physics Department, University of Malaya, 50603 Kuala Lumpur, Malaysia;1. Division of Biosciences, SLAC National Accelerator Laboratory, Stanford, California;2. Departments of Mechanical Engineering and Bioengineering, Stanford University, Stanford, California;1. Department of Bionanotechnology, Gachon University, Seongnam 461701, Republic of Korea;2. WCU Department of Energy Engineering, Hanyang University, Seoul 133-791, Republic of Korea;3. Department of Chemistry, Myongji University, Yongin 449-728, Republic of Korea;4. Department of Energy and Biotechnology, Myongji University, Yongin 449-728, Republic of Korea |
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| Abstract: | The targeting of ferrofluids composed of 20 nm magnetic particles was studied through simulation and animal experiment. The results showed that some magnetic particles were concentrated in the target area depending on the applied magnetic field. Through theoretical analysis, the retention of the magnetic nanoparticles in a target area is due to large magnetic liquid beads formed by the magnetic field. |
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