Generation of 3-pyridyl biaryl systems via palladium-catalyzed Suzuki cross-couplings of aryl halides with 3-pyridylboroxin |
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| Authors: | Cioffi Christopher L Spencer William T Richards Justin J Herr R Jason |
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| Institution: | Medicinal Chemistry Department, Albany Molecular Research Inc., P.O. Box 15098, Albany, NY 12212-5098, USA. chris.cioffi@albmolecular.com |
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| Abstract: | The synthesis of 3-pyridyl biaryl systems can be readily achieved by means of palladium-catalyzed Suzuki cross-coupling reactions between aryl halides and 3-pyridylboroxin. A series of cross-couplings were conducted in order to investigate the scope and limitations of this protocol. |
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