Structural determination of prunusins A and B,new C‐alkylated flavonoids from Prunus domestica,by 1D and 2D NMR spectroscopy |
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| Authors: | Azhar Mahmood Itrat Fatima Shaheen Kosar Rehana Ahmed Abdul Malik |
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| Affiliation: | 1. PNEC National University of Sciences and Technology, Karachi‐75270, Pakistan;2. HEJ Research Institute of Chemistry, University of Karachi, Karachi‐75270, Pakistan;3. Department of Chemistry, University of Karachi, Karachi‐75270, Pakistan |
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| Abstract: | Prunusins A (1) and B (2), the new C‐alkylated flavonoids, have been isolated from the seed kernels of Prunus domestica. Their structures were assigned from 1H and 13C nuclear magnetic resonating spectra, DEPT and by correlation spectroscopy, HMQC and HMBC experiments. 3, 5, 7, 4′‐Tetrahydroxyflavone (3) and 3, 5, 7‐trihydroxy‐8, 4′‐dimethoxyflavone (4) have also been reported from this species. Both compounds (1) and (2) showed significant antifungal activity against pathogenic fungus Trichophyton simmi. Copyright © 2009 John Wiley & Sons, Ltd. |
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| Keywords: | NMR 1D/2D NMR Prunus domestica Rosaceae C‐alkylated flavonoids prunusin A prunusin B |
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