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Copper-catalyzed direct cyanation of terminal alkynes with benzoyl cyanide
Authors:Yan Du  Zheng Li
Institution:College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, Gansu 730070, PR China
Abstract:Copper-catalyzed direct cyanation of terminal alkynes is achieved using less toxic, stable and easy to handle benzoyl cyanide as a cyanide source and air as an oxidant. This protocol provides a good alternative to the preparation of 3-arylpropiolonitriles under mild condition.
Keywords:Terminal alkyne  Benzoyl cyanide  Cyanation  Propiolonitrile
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