Copper-catalyzed direct cyanation of terminal alkynes with benzoyl cyanide |
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Authors: | Yan Du Zheng Li |
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Institution: | College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, Gansu 730070, PR China |
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Abstract: | Copper-catalyzed direct cyanation of terminal alkynes is achieved using less toxic, stable and easy to handle benzoyl cyanide as a cyanide source and air as an oxidant. This protocol provides a good alternative to the preparation of 3-arylpropiolonitriles under mild condition. |
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Keywords: | Terminal alkyne Benzoyl cyanide Cyanation Propiolonitrile |
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