A Freeze Dried Kit for 99mTc(V) Dimercaptosuccinic Acid |
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| Authors: | A Mushtaq Sh Pervez I Haider M S Mansur M Jehangir |
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| Institution: | (1) Radioisotope Production Group, Nuclear Chemistry Division, Pakistan Institute of Nuclear Science and Technology, P.O. Nilore, Islamabad, Pakistan |
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| Abstract: | 99mTc pentavalent dimercaptosuccinic acid 99mTc(V) DMSA], a useful agent for imaging thyroid medullary carcinoma and other tumors can be reliably prepared by addition of Na99mTcO4 to a freeze-dried mixture of DMSA and Sn (2:1 molar ratio). The radiochemical purity, stability and animal bio-distribution behaviour is similar to that of the agent made by addition of NaHCO3 to DMSA (III) renal imaging freeze-dried kit. |
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