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Electrochemically controlled methods for removal of endo- and exotoxicants from biological media |
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| Authors: | M. Sh. Khubutiya A. Yu. Tsivadze M. M. Gol’din V. N. Andreev G. R. Garaeva A. A. Stepanov Mikh. M. Gol’din |
| Affiliation: | 1. N.V. Sklifosovsky Research Institute of Emergency Medicine, B. Sukharevskaya pl. 3, Moscow, 129090, Russia 2. A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, Leninskii pr. 31, Moscow, 119991, Russia 3. Liberty University, 1971 University Blvd, Lynchburg, VA, 95653, USA |
| Abstract: | The electrochemical model of the system of electroconductive hemosorbent/biological medium was proposed to develop electro-chemically controlled medical detoxification technologies for treat-ment of diseases of certain etiology. It was obtained that the destruc-tion of blood cells as a result of a contact blood with hemosorbents is caused of hemosorbent potential. The potential region of hemosor-bent corresponding of hemocompatibility was determined. Hemo-compatible composite material based on activated carbon covered polypyrrole were synthesized. Certain electrochemical medical tech-nologies for selective removing of endo- and exotoxicants and dam-aged blood cells from biological media of organism were developed. |
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