Metal complexes of biological active 2-aminothiazole derived ligands

The most imperative outcomes of extensive sterdies (synthesis, spectral, structural characterization and biological applications) of metal complexes with thiazole derived ligands are reviewed. A large number of coordination compounds are known but still there is a need of new compounds to develop various efforts in different fields for biomedical applications. The synthesis of Schiff base ligands is very important, and it has recently drawn the attention of numerous research groups, making this area constantly evolve. Authors are also synthesizing some novel biologically potent ligands and their unique complexes and complexes found more biological active agents than that of ligands against bacteria, fungi and herbs. Highlights: Schiff bases and their metal chelates catalyze reactions; Schiff bases derived from sulfane thiadiazole show toxicities against insects; Schiff bases of thiadiazole have good plant regulator activity; Phenyl ring attached to the thiazole group showed interesting structure activity.