Chiral calcium catalysts for asymmetric hydroamination/cyclisation |
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Authors: | Wixey James S Ward Benjamin D |
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Institution: | School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff CF10 3AT, UK. |
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Abstract: | Calcium complexes supported by chiral 1,2-diamines have been shown to be efficient catalysts for the asymmetric hydroamination of amino-olefin substrates; the calcium complexes Ca(NN(R)){N(SiMe(3))(2)}(THF)] (R = (t)Bu, (i)Pr, Ph, 4-C(6)H(4)F) give enantioselectivities of up to 26% which marks a significant increase based upon literature precedence. The structure of Ca(NN(Ph)){N(SiMe(3))(2)}(py)] has been computed with density functional methods. |
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