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Enantioselective metallo-organocatalyzed preparation of cyclopentanes bearing an all-carbon quaternary stereocenter
Authors:Montaignac Benjamin  Praveen Chandrasekaran  Vitale Maxime R  Michelet Véronique  Ratovelomanana-Vidal Virginie
Institution:E.N.S.C.P., Chimie-ParisTech, UMR 7223, Laboratoire Charles Friedel (LCF), 75005 Paris, France.
Abstract:Enantioselective metallo-organocatalyzed carbocyclizations of formyl-alkynes have been developed. The cooperation between aminocatalysis and a chiral copper(I) complex granted access to enantio-enriched cyclopentanes through the challenging formation of all-carbon quaternary stereocenters.
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