PEG Click‐Triazole Palladacycle: An Efficient Precatalyst for Palladium‐Catalyzed Suzuki‐Miyaura and Copper‐free Sonogashira Reactions in Neat Water |
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| Authors: | Guofu Zhang Wei Zhang Yuxin Luan Xingwang Han Chengrong Ding |
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| Institution: | College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang 310014, China |
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| Abstract: | A novel water‐soluble, phosphine‐free PEG "click" triazole palladacycle has been successfully synthesized. As a precatalyst, the palladacycle exhibited superior catalytic activity towards Suzuki‐Miyaura and copper‐free Sonogashira cross‐coupling in neat water with the turnover numbers (TONs) of up to 9.8×105. In addition, the catalyst could be reused at least 3 times without significant loss of reactivity. |
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| Keywords: | palladium cross‐coupling palladacycle N‐ligands green chemistry |
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