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Purity control of the radiopharmaceutical thiamine pyrophosphate-Sn-99mTc
Authors:P Busse Grawitz  M C Palcos
Institution:(1) Dirección de Radioisótopos y Radiaciones-Centro Atómico Ezeiza, Comisión Nacional de Energia Atómica, Buenos Ayres, (Argentina)
Abstract:A new purity control method was developed in order to assure the radiochemical purity of thiamine pyrophosphate-Sn-99mTc. The method described consists in ascending cromatography using Whatman No 1 for support and 5% sodium citrate as solvent. It is capable of detecting free99mTcO 4 and colloid formation, the most frequent impurities found in99mTc radiopharmaceuticals.
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