Purity control of the radiopharmaceutical thiamine pyrophosphate-Sn-99mTc |
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Authors: | P Busse Grawitz M C Palcos |
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Institution: | (1) Dirección de Radioisótopos y Radiaciones-Centro Atómico Ezeiza, Comisión Nacional de Energia Atómica, Buenos Ayres, (Argentina) |
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Abstract: | A new purity control method was developed in order to assure the radiochemical purity of thiamine pyrophosphate-Sn-99mTc. The method described consists in ascending cromatography using Whatman No 1 for support and 5% sodium citrate as solvent. It is capable of detecting free99mTcO
4
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and colloid formation, the most frequent impurities found in99mTc radiopharmaceuticals. |
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