| Study on Triplex DNA by Use of Molecular “Light Switch“ Complex of Ru(phen)2(dppx)^2 |
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| 引用本文： | Lian Sheng LING Zhi Ke HE 等. Study on Triplex DNA by Use of Molecular “Light Switch“ Complex of Ru(phen)2(dppx)^2[J]. 中国化学快报, 2003, 14(3): 300-303 |
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| 作者姓名： | Lian Sheng LING Zhi Ke HE 等 |
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| 作者单位： | [1]DepartmentofChemistry,WuhanUniversity,Wuhan430072 [2]InstituteofChemistry,TheChineseAcademyofSciences,Beijing100080 |
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| 摘 要： | A new method for the study of triplex DNA is established according the fluorescence enhancement of molecular “Light Switch“ complex of Ru(phen)2(dppx)^2 when it intercalate into triplex DNA.Because the fluorescence intensity of Ru(phen)2(dppx)^2 bonded to triplex DNA is in ths case higher than that bonded to duplex DNA in certain range of DNA concentration,the method is much more sensitive than other methods reported previously.
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| 关 键 词： | DNA 钌配合物 分子光开关 结构 生物化学 相互作用 键合能 |
Study on Triplex DNA by Use of Molecular "Light Switch" Complex of Ru(phen)2(dppx)2+ |
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| Lian Sheng LING,Zhi Ke HE,Fang CHEN,Hua Shan ZHANG,Yun E ZENG. Study on Triplex DNA by Use of Molecular "Light Switch" Complex of Ru(phen)2(dppx)2+[J]. Chinese Chemical Letters, 2003, 14(3): 300-303 |
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| Authors: | Lian Sheng LING Zhi Ke HE Fang CHEN Hua Shan ZHANG Yun E ZENG |
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| Abstract: | A new method for the study of triplex DNA is established according the fluorescence enhancement of molecular "Light Switch" complex of Ru(phen)2(dppx)2+ when it intercalate into triplex DNA. Because the fluorescence intensity of Ru(phen)2(dppx)2+ bonded to triplex DNA is in the case higher than that bonded to duplex DNA in certain range of DNA concentration, the method is much more sensitive than other methods reported previously. |
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| Keywords: | Ru(phen)2(dppx)2+ molecular " Light Switch" triplex DNA |
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