Catalysis of Ugi four component coupling reactions by rare earth metal triflates |
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Authors: | Okandeji Babajide O Gordon Jonathan R Sello Jason K |
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Affiliation: | Department of Chemistry, Brown University, 324 Brook Street, Providence, Rhode Island 02912, USA. |
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Abstract: | Substoichiometric quantities of scandium and ytterbium triflate increase the yield of Ugi four component coupling reactions of aromatic aldehydes 2- to 7-fold. These rare earth metal triflates enhance the reaction yields primarily via activation of the imine intermediate of this multicomponent reaction. |
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