Green Approach to the Design of Functionalized Medicinally Privileged 4‐Aryl‐1,4‐dihydropyrano[2,3‐c]‐pyrazole‐5‐carbonitrile Scaffold |
| |
| Authors: | Alexey I. Ilovaisky Michael G. Medvedev Valentina M. Merkulova Michail N. Elinson Gennady I. Nikishin |
| |
| Affiliation: | N. D. Zelinsky Institute of Organic Chemistry, Moscow, Russia |
| |
| Abstract: | “On water” multicomponent condensation of aromatic aldehydes, malononitrile, and 3‐methyl‐2‐pyrazoline‐5‐one in the presence of sodium hydroxide as catalyst leads to 6‐amino‐3‐methyl‐4‐aryl‐1,4‐dihydropyrano[2,3‐c]pyrazole‐5‐carbonitriles in 85–98% yields. |
| |
| Keywords: | |
|
|
