An Efficient Ultrasound‐Assisted Synthesis of N‐Alkyl Derivatives of Carbazole,Indole, and Phenothiazine |
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| Authors: | Sanhu Zhao Jin Kang Yuting Du Jingyan Kang Xiaoni Zhao Yinfeng Xu Ruixi Chen Qianqian Wang Xitao Shi |
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| Affiliation: | Department of Chemistry, Xinzhou Teachers University, Xinzhou, China |
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| Abstract: | Heterocyclic compounds bearing an acidic hydrogen atom attached to nitrogen such as carbazole, indole, and phenothiazine can be efficiently alkylated in DMSO or N,N‐DMF under ultrasonic irradiation in the presence of potassium hydroxide as a base. In almost all cases, a dramatic reduction of the reaction time results and a clear yield increase accompanied by an improved quality of the products occurs. |
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