Four‐Component,One‐Pot Synthesis of 1,4‐Disubstituted 1,2,3‐Triazoles Bearing 1‐(2‐Phenylselenocyclohexyl) Group |
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| Authors: | Wusheng Sheng Shouri Sheng Jiangbo Zeng Zhenzhong Huang Mingzhong Cai |
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| Institution: | Key Laboratory of Functional Small Organic Molecule, Ministry of Education, Jiangxi Normal University, Jiangxi, Nanchang, People's Republic of China |
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| Abstract: | An efficient, one‐pot, three‐step, regioselective synthesis of 4‐substituted 1‐(2‐phenylselenocyclohexyl)‐1,2,3‐triazoles, involving in situ generation of l‐azido‐2‐phenylselenocyclohexane has been developed via four‐component reaction of phenylselenenyl bromide, cyclohexene, sodium azide and terminal alkynes catalyzed by copper iodide in a mixture of DMF/THF (1:1) at room temperature under mild conditions with simple workup and good yields. |
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