A New Iodonium Ylide‐Based Three‐Component Reaction Leading to 2‐Spirosubstituted Dihydrofurans under Microwave Irradiation |
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| Authors: | Xing‐Chao Tu Yan Yu Man‐Su Tu Bo Jiang Chao Li Shu‐Jiang Tu |
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| Affiliation: | School of Chemistry & Chemical Engineering, and Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou, Jiangsu, People's Republic of China |
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| Abstract: | A new iodonium ylide‐based three‐component reaction for the synthesis of highly functionalized 2‐spirosubstituted dihydrofurans starting from readily available common reactants has been developed under microwave irradiation. The procedure is facile, avoiding time‐consuming and costly syntheses, tedious work‐up and purifications of precursors as well as protection/deprotection of functional groups. This method is very efficient because of short reaction times and easy work‐up and provides an efficient strategy for the construction of the polysubstituted spiro dihydrofuran skeleton. |
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