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One‐Pot Synthesis of New 1,5‐Disubstituted Tetrazoles Bearing 2,2‐Bis(trimethylsilyl)ethenyl Groups via The Ugi Four‐Component Condensation Reaction Catalyzed by MgBr2·2Et2O
Authors:Kazem D. Safa  Tohid Shokri  Hassan Abbasi  Reza Teimuri‐Mofrad
Affiliation:Organosilicon Research Laboratory, Faculty of Chemistry, University of Tabriz, Tabriz, Iran
Abstract:A simple one‐pot Ugi four‐component condensation reaction has been developed for the synthesis of tetrazoles bearing 2,2‐bis(trimethylsilyl)ethenyl groups from the synthesized 4‐[2,2‐bis(trimethylsilyl) ethenyl]benzaldehyde ( 1 ), various amines, isocyanides, and trimethylsilylazide at room temperature, without solvent, and in the presence of catalytic amounts of MgBr2·2Et2O as catalyst.
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