Larrealignans A and B, novel lignan glycosides from the aerial parts of Larrea tridentata |
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| Authors: | Yokosuka Akihito Matsuo Yukiko Jitsuno Maki Adachi Kohei Mimaki Yoshihiro |
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| Institution: | Laboratory of Medicinal Pharmacognosy, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Hachioji, Tokyo, Japan. yokosuka@toyaku.ac.jp |
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| Abstract: | Two new lignan glycosides, named larrealignans A (1) and B (2), and a known lignan (3) were isolated from the aerial parts of Larrea tridentata (Zygophyllaceae). The structures of 1 and 2 were determined on the basis of spectroscopic analysis and the results of hydrolytic cleavage. The isolated compounds (1-3) and aglycones (1a, 2a) of 1 and 2 were evaluated for their cytotoxic activities against HL-60 human leukemia cells. |
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