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Synthesis and characterization of PISOZ-PDMS-PISOZ triblock polymer vesicles
Authors:Haike Feng  Xiaoxiu Yu
Institution:1. College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, Zhejiang, Chinafhkfhk@163.com;3. College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University, Hangzhou, Zhejiang, China
Abstract:In this project, we synthesized poly(2-isopropyl-2-oxazoline)-block- poly(dimethyl-siloxane)-block-poly(2-isopropyl-2-oxazoline) (PISOZ-PDMS-PISOZ) triblock polymer, which has been prepared as vesicles. The triblock polymer was characterized by 1H-NMR, F-NMR, LS and TEM. The size of the empty vesicle is about 60 nm. When curcumin was encapsulated into PISOZ-PDMS-PISOZ triblock polymer, formed well defined vesicles in a size about 70 nm.
Keywords:Curcumin  poly(dimethylsiloxane)  triblock polymer  vesicle
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