| Differential pulse voltammetric studies on the effects of Al（Ⅲ） on the lactate dehydrogenase activity |
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| 作者姓名： | Kai An Yao Na Wang Jing Yue Zhuang Zheng Biao Yang Hai Yan Ni Quan Xu Cheng Sun Shu Ping Bi |
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| 作者单位： | State Key Laboratory of Pollution Control and Resource Reuse ＆ Key Laboratory of MOE for Life Science,School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China |
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| 基金项目： | Acknowledgments This project supported by the Natural Science Foundation of Jiangsu Province （BK 2005083）, Grant of Analytical Measurements of Nanjing University, The National Science Foundation of China （No. 20575025） and Research Funding for the Doctoral Program of Higher Education （No. 20050284030）. |
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| 摘 要： | In this paper, differential pulse voltammetry (DPV) was applied to study the effects of aluminum Al(Ⅲ) on the lactate dehydrogenase (LDH) activity. Michaelis–Menten constant (KmN ADH) and maximum velocity (vmax) in the enzyme promoting catalytic reaction of "pyruvate(Pyr) NADH H LDDHlactate NAD " under different conditions by monitoring DPV reduction current of NAD were reported.
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| 关 键 词： | Al(Ⅲ) DPV Lactate dehydrogenase Biomarker |
| 收稿时间： | 4 January 2007 |
| 修稿时间： | 2007-01-04 |
Differential pulse voltammetric studies on the effects of Al(III) on the lactate dehydrogenase activity |
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| Kai An Yao Na Wang Jing Yue Zhuang Zheng Biao Yang Hai Yan Ni Quan Xu Cheng Sun Shu Ping Bi.Differential pulse voltammetric studies on the effects of Al(III) on the lactate dehydrogenase activity[J].Chinese Chemical Letters,2007,18(7):857-860. |
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| Authors: | Kai An Yao Na Wang Jing Yue Zhuang Zheng Biao Yang Hai Yan Ni Quan Xu Cheng Sun Shu Ping Bi State Key Laboratory of Pollution Control and Resource Reuse & Key Laboratory of MOE for Life Science School of Chemistry and Chemical Engineering Nanjing University Nanjing China |
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| Institution: | Kai An Yao,Na Wang,Jing Yue Zhuang,Zheng Biao Yang,Hai Yan Ni,Quan Xu,Cheng Sun,Shu Ping Bi State Key Laboratory of Pollution Control and Resource Reuse & Key Laboratory of MOE for Life Science,School of Chemistry and Chemical Engineering,Nanjing University,Nanjing 210093,China |
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