| 从脯氨酸合成一种三齿手性配体及其在二乙基锌对醛的对映选择性加成中的应用 |
| |
| 引用本文： | 邱丽华,沈宗旋,葛健锋,张雅文. 从脯氨酸合成一种三齿手性配体及其在二乙基锌对醛的对映选择性加成中的应用[J]. 中国化学, 2005, 23(7): 898-900. DOI: 10.1002/cjoc.200590898 |
| |
| 作者姓名： | 邱丽华 沈宗旋 葛健锋 张雅文 |
| |
| 作者单位： | [1]KeyLaboratoryofOrganicSynthesisofJiangsuProvince,CollegeofChemistryandChemicalEngineering,SuzhouUniversity,Suzhou,Jiangsu215006,China [2]SchoolofMaterialandEngineering,SuzhouUniversity,Suzhou,Jiangsu215006,China |
| |
| 摘 要： | A new chiral tridentate ligand [1-(1-methyl-S-pyrrolidin-2-ylmethyl)-S-pyrrolidin-2-yl]-diphenylmethanol (1) has been successfully synthesized from S-proline. The structure of the ligand was characterized by NMR spectra and X-ray diffraction analysis. Its catalytic ability has also been examined in enantioselective addition of diethylzinc towards aldehydes with 15%-84% enantiomeric excesses (ee).
|
| 关 键 词： | 合成 手性三齿配位体 脯氨酸 对映选择性加成反应 二乙基锌 乙醛 X射线衍射 |
| 收稿时间： | 2004-09-06 |
| 修稿时间： | 2005-03-21 |
Synthesis of a Chiral Tridentate Ligand from Proline and Its Application to Enantioselective Addition of Diethylzinc to Aldehydes |
| |
| Qiu Li‐Hua,Shen Zong‐Xuan,Ge Jian‐Feng,Zhang Ya‐Wen. Synthesis of a Chiral Tridentate Ligand from Proline and Its Application to Enantioselective Addition of Diethylzinc to Aldehydes[J]. Chinese Journal of Chemistry, 2005, 23(7): 898-900. DOI: 10.1002/cjoc.200590898 |
| |
| Authors: | Qiu Li‐Hua Shen Zong‐Xuan Ge Jian‐Feng Zhang Ya‐Wen |
| |
| Abstract: | A new chiral tridentate ligand [1‐(1‐methyl‐S‐pyrrolidin‐2‐ylmethyl)‐S‐pyrrolidin‐2‐yl]‐diphenylmethanol ( 1 ) has been successfully synthesized from S‐proline. The structure of the ligand was characterized by NMR spectra and X‐ray diffraction analysis. Its catalytic ability has also been examined in enantioselective addition of diethylzinc towards aldehydes with 15%–84% enantiomeric excesses (ee). |
| |
| Keywords: | chiral tridentate ligand X‐ray diffraction enantioselective addition diethylzinc |
| 本文献已被 维普 等数据库收录！ |
| 点击此处可从《中国化学》浏览原始摘要信息 |
|
点击此处可从《中国化学》下载全文 |
