Phenyl radicals react with dinucleoside phosphates by addition to purine bases and H-atom abstraction from a sugar moiety |
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Authors: | Liu Ji-ang Petzold Christopher J Ramirez-Arizmendi Luis E Perez James Kenttämaa Hilkka |
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Institution: | Department of Chemistry, Purdue University, 560 Oval Drive, West Lafayette, Indiana 47907-2038, USA. |
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Abstract: | Laser-induced acoustic desorption combined with mass spectrometry has been used to demonstrate that phenyl radicals can attack dinucleoside phosphates at both the sugar and base moieties, that purine bases are more susceptible to the attack than pyrimidine bases, and that the more electrophilic the radical, the more efficient the damage to dinucleoside phosphates. |
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